Miscellaneous We see a wide variety of diseases affecting the skin, ears and nails that are not so easily categorized. Zinc responsive dermatosis causes thick crusts to appear around the lids. Hepatocutaneous syndrome is a skin disease that occurs secondary to severe internal disease. This dog had burns after the tea fire in Santa Barbara. Lamellar ichthyosis is a genetic disease that causes dramatic skin flakes. There are a number of disease that can cause abnormal nails.